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Showing posts from August, 2023

Blast And its Types

Special kinds of BLASTs In addition to the standard BLAST algorithms (BLASTn, BLASTp, BLASTx, tBLASTn, tBLASTx), there are several special kinds of BLASTs that have been developed to address specific needs in sequence analysis. Here are a few examples: Advertisements Advertisements PSI-BLAST (Position-Specific Iterated BLAST):  PSI-BLAST is an iterative version of BLASTp that aims to improve the detection of distantly related protein sequences. It builds a position-specific scoring matrix (PSSM) based on the alignments found in previous iterations, allowing for the identification of more divergent homologs. Advertisements PHI-BLAST (Pattern-Hit Initiated BLAST):  PHI-BLAST is used for identifying and aligning protein sequences that contain specific patterns or motifs. It starts with a pattern search against a protein database and then extends the search using a BLAST-like algorithm. DELTA-BLAST:  DELTA-BLAST is a tool that combines the advantages of PSI-BLAST and HMMER. It performs a s

DNA Vs RNA

DNA vs RNA – Similarities and Differences in directiThree differences between DNA and RNA are that DNA uses the base thymine while RNA uses uracil, DNA uses the sugar deoxyribose while RNA uses ribose, and usually DNA is double-stranded and RNA is single-stranded DNA  (deoxyribonucleic acid) and  RNA  (ribonucleic acid) are the two types of  nucleic acids  found in cells. Nucleic acids, in turn, are the biological molecules that code for genetic infor mation and proteins. Here is a comparison of the similarities and differences between DNA and RNA. e are different types of DNA and RNA. DNA occurs in five forms: A-DNA, B-DNA, C-DNA, D-DNA, and Z-DNA. The B form occurs in most organisms and is a right-handed helix with a major and minor groove. The main types of RNA are messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA). Many additional types of RNA also exist. A cell typically contains one type of DNA and several forms of RNA.   Differences Between DNA and RNA DNA and R